Protecting the heart and brain of menopausal women

IRM
Project lead
Dre Claudine Gauthier
Dr. Claudine Gauthier
researcher in magnetic resonance imaging
Potential impact
Slow down the development of vascular and cerebral diseases during menopause through prevention.
How menopause affects a woman’s heart and brain health is still not fully understood. In addition to relieving the symptoms associated with menopause, hormone therapy could also prevent heart conditions and cognitive impairment caused by hormonal changes. Dr. Claudine Gauthier’s research project aims to demonstrate that a viable solution for women could exist.

Observation

Observation

Safeguarding menopausal women

A woman’s risk of developing heart disease increases considerably during menopause.

Prior to menopause, estrogen and other sex hormones play a protective role on the heart, blood vessels, and brain.

As hormone levels decline, this natural protection diminishes. The impact of this transition on a woman’s vascular and brain health is not completely clear.

Goal

The key to prevention lies in knowledge

Dr. Claudine Gauthier's project investigates how menopause and hormone therapy impact the heart and brain health of women.

Her team uses magnetic resonance imaging to study women between the ages of 30 and 60, categorized according to their hormonal phase and whether they are undergoing hormone therapy or not. Each participant undergoes a series of assessments including cognitive tests, exercise tests, vascular health measurements, and brain scans.

This approach allows Dr. Gauthier to evaluate the impact of hormone loss on blood vessels and assess the role of hormone therapy and an active lifestyle in prevention.

“The symptoms of menopause — fatigue, depression, anemia, weight gain, etc. — can be difficult to deal with. Currently, hormone therapy is only prescribed to alleviate hot flashes. What if it could also be prescribed earlier to limit the risk of developing vascular and cerebral diseases?”
[Dr. Claudine Gauthier, researcher in magnetic resonance imaging]

Impact

A tangible impact on women’s health

The same recommendations are often issued to everyone. But it is vital that a woman’s biology be taken into account if we want to find solutions adapted to them. Thanks to this research project, hormone therapy could not only be used to relieve the symptoms of menopause, but also to: 

  • Prevent cognitive decline
  • Reduce the risk of heart disease

Dr. Gauthier’s research provides a new perspective that will increase our understanding of vascular aging and optimize prevention strategies for women’s health.

40%
40% of Canadian women could benefit from this therapy